Disease Management

There is currently no cure for Alpha Mannosidosis, and treatment is often limited to addressing or controlling symptoms.1

Recommendation for symptoms management

A proactive approach is adopted to prevent any emerging complications, and a thorough clinical assessment is carried out at the time of initial diagnosis.2

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Specific management options

Rationale for treatment: with this condition, all cells are without α-mannosidase activity. The rationale for HSCT in this setting is that enzyme-producing donor cells repopulate the host tissues and transfer enzyme to nearby enzyme-deficient host cells.

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  1. Malm D & Nilssen Ø. Alpha-mannosidosis. Orphanet J Rare Dis 2008;3:21
  2. Malm D & Nilssen Ø. Alpha-mannosidosis. Orphanet J Rare Dis 2008;3:21

The information on this website is intended only to provide knowledge of Alpha Mannosidosis disease health topics. This information should not be used in place of advice from your GP or other healthcare professional. If in doubt please contact your doctor for advice. This website has been produced by Chiesi Pharmaceuticals. The website has been developed in accordance with industry and legal standards to provide information for healthcare professionals and the general public about Alpha Mannosidosis disease health topics. Chiesi Pharmaceuticals makes every reasonable effort to include accurate and current information. However, the information provided in this website is not exhaustive.